Focused on the molecular basis of human cancers, our research team has deciphered liver cancer expression profiles and metastasis associated genes. Ongoing research includes the identification of potential therapeutic targets, growth factor granulin-epithelin precursor (GEP) and its roles in cancer growth, invasion, drug resistance, cancer stemness properties and antibody targeted therapy.

We have extended our studies from genomics to examining novel molecular biomarkers on diagnostic with prognostic implication. Current research focuses on natural killer cell-mediated cytotoxicity against tumour cells and rational combination therapy to improve treatment efficacy.

Nathalie WONG   |   natwongadd this for spam@add this for spamcuhk.edu.hk  

Bioengineering or biomedical engineering is the application of engineering principles and design concepts in medicine and biology for healthcare. This field is narrowing the gap between engineering and medicine, combining the design and problem-solving skills of engineering with biomedical sciences to advance healthcare treatments.

Our current areas of research interest include wearable sensing, endoscopic informatics and smart cancer screening. We develop innovative medical devices and robotics, including flexible surgical instruments/robotics, soft medical robotics and magnetic anchored and guided systems. In addition, we are studying visceral biomechanics,gastrointestinal (GI) mechanosensory properties, the development of endoluminal devices for the treatment of obesity, and diagnostics of functional GI disorders.

We use experimental and computational approaches to address surgically relevant healthacre problems and have published our findings in leading bioengineering and medical journals. Currently, we are focused on development of several medical devices for diagnostics and therapy, including performance and validation studies, and proof-of-concept clinical trials.

Zheng LI   |   zliadd this for spam@add this for spamsurgery.cuhk.edu.hk  

We aim to converge our strengths in genomics, bioinformatics, biological, preclinical and clinical research to developing and validating novel molecular biomarkers with diagnostic, subtyping, prognostic and/or predictive implications, and novel therapeutics for better treatment of major human diseases such as cancers.

We have been focusing on mechanistic and translational research in major human diseases by developing novel methodologies integrating bioinformatics, systems biology, machine learning and artificial intelligence. Represented by our significant contribution to the establishment of the consensus colorectal cancer subtyping (CMS) system, we have developed and validated various molecular and image-based biomarkers for early detection of cancer, subtyping, prognostication, prediction, and monitoring of therapeutic response. Together with our academic surgeons, who have rich experience in clinical studies in their respective areas, we have been working closely on validating novel diagnostics and therapeutics based on various clinical studies.

Xin WANG   |   xwangadd this for spam@add this for spamsurgery.cuhk.edu.hk