Department of Surgery, CUHK


The Division of Upper Gastrointestinal and Metabolic Surgery (Team II) is world renowned for its research in the surgical treatment of a great variety of upper gastrointestinal tract diseases, endocrine disorders and metabolic diseases associated with obesity. In conjunction with the Endoscopy Centre, we are also a leading unit in advanced Endoscopic Retrograde Cholangiopancreatography (ERCP), Endoscopic Ultrasound (EUS), submucosal endoscopy and the management of upper gastrointestinal bleeding.


The Division of Upper Gastrointestinal and Metabolic Surgery (Team II) provides elective and emergency general surgery services for the New Territory East Cluster (NTEC) population in Hong Kong. We also provide subspecialty support for Hong Kong as a Territory referral centre of Upper Gastrointestinal (GI) surgery and advanced therapeutic endoscopy. We are one of the recognized sub-speciality training centres on Upper GI Surgery by the Hong Kong College of Surgeons. Moreover, our Metabolic & Bariatric Surgery centre provides multi-disciplinary team services for patients with morbid obesity and uncontrolled diabetes mellitus. In addition, our Endocrine unit also provides surgical management of various endocrine disorders including neuroendocrine tumour, thyroid, parathyroid and adrenal diseases. In collaboration with our Gastroenterologists, our Endoscopy Centre provides 24 hours services in endoscopic management of GI diseases which include advanced therapeutic upper endoscopy (OGD), Colonoscopy, ERCP and EUS.


Upper Gastrointestinal Surgery:

  • Robotic surgery in the treatment of gastro-oesophageal diseases.
  • Enhanced Recovery After Surgery (ERAS) program on laparoscopic gastrectomy for stomach cancer.
  • Epigenetic changes in squamous cell carcinoma of the oesophagus.
  • Electro-acupuncture for gastro-oesophageal reflux diseases.
  • Efficacy and safety of laparoscopic anti-reflux procedures for GERD in Chinese.
  • Trans-arterial embolisation for high risk bleeding peptic ulcer.

Advanced Therapeutic Endoscopy:

  • Over-the-Scope Clip for upper gastrointestinal bleeding.
  • Anti-reflux Mucosectomy (ARMS) for gastro-oesophageal reflux disease.
  • Submucosal endoscopy.
  • Therapeutic interventional EUS.
  • Endoscopic sleeve gastroplasty (ESG) for morbid obesity.

Metabolic & Bariatric Surgery:

  • Sleeve gastrectomy with loop duodenojejunostomy versus Roux-en Y gastric bypass in obese uncontrolled type 2 diabetes.
  • Prophylactic Anterior Crural repair in prevention of De Novo gastroesophageal reflux after sleeve gastrectomy.
  • Clinical course and biomarkers associated with nonalcoholic fatty liver disease (NAFLD) in Chinese patients with obesity.
  • Integrated genetic, epigenetic and clinical trait-based model for predicting metabolic surgery responses.


The Team has established itself as a world leading centre in research & our publications are regularly featured in top grade journals. Not only are our publications widely cited, their findings have made major impact in clinical practices:

  1. Endoscopic therapy for upper GI bleeding
    • Injection therapy of bleeding peptic ulcers.
    • Refinement of endoscopic techniques in treatment of bleeding oesophageal varices.
    • Clinical trials in the use of antibiotics alone against Helicobacter pylori associated peptic ulcers without acid suppression.
  2. Advance endoscopic therapy for GI diseases in Hong Kong
    • Endoscopic submucosal dissection (ESD) for GI early cancers.
    • Peroral Endoscopic Myotomy (POEM) for achalasia.
    • Advanced ERCP techniques.
    • EUS-guided interventions including drainage of pancreatic fluid collections, biliary and gallbladder drainage, gastroenterostomy and other interventions.
  3. Surgical & endoscopic therapy for obesity & diabetes in Hong Kong
    • Introduction of gastric band, sleeve gastrectomy and gastric bypass surgery.
    • Introduction of endoscopic bariatric therapy - intragastric balloon & endoscopic sleeve gastroplasty.
  4. Advancement of Minimally Invasive treatment for Endocrine Diseases
    • CT-guided radiofrequency ablation in treatment of benign adrenal neoplasms.
    • Endoscopic / Robotic / Transoral thyroidectomy for thyroid neoplasms.

Apart from clinical research, our Team provides Continued Medical Education through organization of local, regional & international workshops.

  • Since 1985, our International Therapeutic Endoscopy Workshop has attracted hundreds of participants from around the world each year to join.
  • We have organised hundreds of workshops in minimally invasive and robotic surgery leading to propagation of the technique in the Asian-Pacific region.

In an ever-evolving healthcare landscape, we endeavour to continue our dedication and passion to clinical and laboratory research. In addition, we will continue our central role in providing medical education in the Asian-Pacific region.

Academic Staff
Professor NG Kwok Wai Enders Professor
Professor CHIU Wai Yan Philip Shun Hing Education and Charity Fund Professor of Robotic Surgery
Dr CHAN Shannon Melissa Assistant Professor
Dr YIP Hon Chi Assistant Professor
HA Staff
Dr LIU Yuk Wah Shirley Consultant
Dr NG Ka Kei Stephen Consultant
Dr LEUNG Lai Ying Sandy Associate Consultant
Dr HAU Siew Fung Victor Resident
Dr FOK Chi Ying Jacquelyn Resident
Dr NG Wing Fung Jonathan Resident
Dr HUI Ming Hon Matthew Resident
Dr LAU Yu Him Zachary Resident
Dr LEE Ka Yu Fish Resident
Dr LUI Joshua Resident
Dr CHEUNG Tsz King Johnny Resident


Peroral Endoscopic Myotomy

ICG Guided Minimally Invasive Oesophagectomy

EUS Guided Gallbladder Drainage

EUS Guided Gastroenterostomy

3D Laparoscopic Surgery

Robotic Gastrectomy

Endoluminal Robotics

The Scalpel and the Brush - June 2019

First Robotic Endoscopic Scarless Surgery in HK

Scarless Per-oral Endoscopic Myotomy


COVID-related Publications

  • Shabbir A, Menon RK, Somani J, So JBY, Ozman M, Chiu PWY, Lomanto D.
    ELSA recommendations for minimally invasive surgery during a community spread pandemic: a centered approach in Asia from widespread to recovery phases.
    Surg Endosc. 2020 Aug;34(8):3292-3297
  • Chan SM, Ma TW, Ka-Chun Chong M, Chan DL, Ng EKW, Chiu PWY.
    A proof of concept study: Esophagogastroduodenoscopy is an aerosol-generating procedure and continuous oral suction during the procedure reduces the amount of aerosol generated.
    Gastroenterology. 2020 Jul 7:S0016-5085(20)34919-2. doi: 10.1053/j.gastro.2020.07.002. Online ahead of print.
  • Keswani RN, Sethi A, Repici A, Messmann H, Chiu PW.
    How To Maximize Trainee Education During the Coronavirus Disease-2019 Pandemic: Perspectives From Around the World.
    Gastroenterology. 2020 Jul;159(1):26-29.
  • Soetikno R, Teoh AY, Kaltenbach T, Lau JY, Asokkumar R, Cabral-Prodigalidad P, Shergill A.
    Considerations in performing endoscopy during the COVID-19 pandemic.
    Gastrointest Endosc. 2020 Jul;92(1):176-183. doi: 10.1016/j.gie.2020.03.3758. Epub 2020 Mar 27.
  • Chiu PWY, Ng SC, Inoue H, Reddy DN, Ling Hu E, Cho JY, Ho LK, Hewett DG, Chiu HM, Rerknimitr R, Wang HP, Ho SH, Seo DW, Goh KL, Tajiri H, Kitano S, Chan FKL.
    Practice of endoscopy during COVID-19 pandemic: position statements of the Asian Pacific Society for Digestive Endoscopy (APSDE-COVID statements).
    Gut. 2020 Jun;69(6):991-996.
  • Balakrishnan K, Schechtman S, Hogikyan ND, Teoh AYB, McGrath B, Brenner MJ.
    COVID-19 Pandemic: What Every Otolaryngologist-Head and Neck Surgeon Needs to Know for Safe Airway Management.
    Otolaryngol Head Neck Surg. 2020 Apr 14:194599820919751.
  • Lui RN, Tang RS, Chiu PW.
    Striving to protect patients and healthcare professionals in endoscopy units during pandemics: from SARS to COVID-19.
    Gastroenterology. 2020 May 5:S0016-5085(20)30594-1. doi: 10.1053/j.gastro.2020.05.002. Online ahead of print.

Advanced Diagnostic and Therapeutic Endoscopy

  • Teoh AYB, Kitano M, Itoi T, Pérez-Miranda M, Ogura T, Chan SM, Serna-Higuera C, Omoto S, Torres-Yuste R, Tsuichiya T, Wong KT, Leung CH, Chiu PWY, Ng EKW, Lau JYW.
    Endosonography-guided gallbladder drainage versus percutaneous cholecystostomy in very high-risk surgical patients with acute cholecystitis: an international randomised multicentre controlled superiority trial (DRAC 1).
    Gut. 2020 Jun;69(6):1085-1091.
  • Chong CCN, Lakhtakia S, Nguyen N, Hara K, Chan WK, Puri R, Almadi MA, Ang TL, Kwek A, Yasuda I, Doi S, Kida M, Wang HP, Cheng TY, Jiang Q, Yang A, Chan AWH, Chan S, Tang R, Iwashita T, Teoh AYB.
    Endoscopic ultrasound-guided tissue acquisition with or without macroscopic on-site evaluation: randomized controlled trial.
    Endoscopy. 2020 Jun 4. doi: 10.1055/a-1172-6027. Online ahead of print.
  • Teoh AYB, Leung CH, Tam PTH, Au Yeung KKY, Mok RCY, Chan DL, Chan SM, Yip HC, Chiu PWY, Ng EKW.
    EUS-guided gallbladder drainage versus laparoscopic cholecystectomy for acute cholecystitis: a propensity score analysis with 1-year follow-up data.
    Gastrointest Endosc. 2020 Jun 29:S0016-5107(20)34532-6. doi: 10.1016/j.gie.2020.06.066. Online ahead of print.
  • Wong GLH, Lau LHS, Ching JYL, Tse YK, Ling RHY, Wong VWS, Chiu PWY, Lau JYW, Chan FKL.
    Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial.
    Gut. 2020 Apr;69(4):652-657.
  • Teoh AYB, Bapaye A, Lakthakia S, Ratanachu T, Reknimitr R, Chan SM, Choi HJ, Gadhikar HP, Kongkam P, Korrapati SK, Lee YN, Medarapalem J, Ridtitid W, Moon JH.
    Prospective multicenter international study on the outcomes of a newly developed self-approximating lumen apposing metallic stent for drainage of pancreatic fluid collections and endoscopic necrosectomy.
    Dig Endosc. 2020 Mar;32(3):391-398.
  • Khashab MA, Sanaei O, Rivory J, Eleftheriadis N, Chiu PWY, Shiwaku H, Ogihara K, Ismail A, Abusamaan MS, El Zein MH, Wong VW, Billioux VG, Kumbhari V, Kalloo AN, Ponchon T, Pioche M.
    Peroral endoscopic myotomy: anterior versus posterior approach: a randomized single-blinded clinical trial.
    Gastrointest Endosc. 2020 Feb;91(2):288-297.e7

  • Xia X, Chan KF, Wong GTY, Wang P, Liu L, Yeung BPM, Ng EKW, Lau JYW, Chiu PWY.
    Mesenchymal stem cells promote healing of nonsteroidal anti-inflammatory drug-related peptic ulcer through paracrine actions in pigs.
    Sci Transl Med. 2019 Oct 30;11(516):eaat7455.
  • Teoh AY, Seo DW, Brugge W, Dewitt J, Kongkam P, Linghu E, Moyer MT, Ryu JK, Ho KY.
    Position statement on EUS-guided ablation of pancreatic cystic neoplasms from an international expert panel.
    Endosc Int Open. 2019 Sep;7(9):E1064-E1077
  • Luk SW, Irani S, Krishnamoorthi R, Wong Lau JY, Wai Ng EK, Teoh AY.
    Endoscopic ultrasound-guided gallbladder drainage versus percutaneous cholecystostomy for high risk surgical patients with acute cholecystitis: a systematic review and meta-analysis.
    Endoscopy. 2019 Aug;51(8):722-732.
  • Ponds FA, Fockens P, Lei A, Neuhaus H, Beyna T, Kandler J, Frieling T, Chiu PWY, Wu JCY, Wong VWY, Costamagna G, Familiari P, Kahrilas PJ, Pandolfino JE, Smout AJPM, Bredenoord AJ.
    Effect of Peroral Endoscopic Myotomy vs Pneumatic Dilation on Symptom Severity and Treatment Outcomes Among Treatment-Naive Patients with Achalasia: A Randomized Clinical Trial.
    JAMA. 2019 Jul 9;322(2):134-144.
  • Chiu PWY, Uedo N, Singh R, Gotoda T, Ng EKW, Yao K, Ang TL, Ho SH, Kikuchi D, Yao F, Pittayanon R, Goda K, Lau JYW, Tajiri H, Inoue H.
    An Asian consensus on standards of diagnostic upper endoscopy for neoplasia.
    Gut. 2019 Feb;68(2):186-197.
  • Zhang Y, Zhang L, Yang L, Vong CI, Chan KF, Wu WKK, Kwong TNY, Lo NWS, Ip M, Wong SH, Sung JJY, Chiu PWY, Zhang L.
    Real-time tracking of fluorescent magnetic spore-based microrobots for remote detection of C. diff toxins.
    Sci Adv. 2019 Jan 11;5(1):eaau9650.
  • Teoh AYB, Dhir V, Kida M, Yasuda I, Jin ZD, Seo DW, Almadi M, Ang TL, Hara K, Hilmi I, Itoi T, Lakhtakia S, Matsuda K, Pausawasdi N, Puri R, Tang RS, Wang HP, Yang AM, Hawes R, Varadarajulu S, Yasuda K, Ho LKY.
    Consensus guidelines on the optimal management in interventional EUS procedures: results from the Asian EUS group RAND/UCLA expert panel.
    Gut. 2018 Jul;67(7):1209-1228. doi: 10.1136/gutjnl-2017-314341. Epub 2018 Feb 20.
  • Chen YI, Inoue H, Ujiki M, Draganov PV, Colavita P, Mion F, Romanelli J, Chiu P, Balassone V, Patel L, Abbas A, Yang D, Dunst C, Pioche M, Roman S, Rivory J, Ponchon T, Desilets D, Maselli R, Onimaru M, Nakamura J, Hata Y, Hajiyeva G, Ismail A, Ngamruengphong S, Bukhari M, Chavez YH, Kumbhari V, Repici A, Khashab MA.
    An international multicenter study evaluating the clinical efficacy and safety of per-oral endoscopic myotomy in octogenarians.
    Gastrointest Endosc. 2018 Apr;87(4):956-961. doi: 10.1016/j.gie.2017.02.007. Epub 2017 Feb 21.
  • Teoh AYB, Chan SM, Yip HC, Wong VWY, Chiu PWY, Ng EKW.
    Randomized controlled trial of EndoWrist-enabled robotic versus human laparoendoscopic single-site access surgery (LESS) in the porcine model.
    Surg Endosc. 2018 Mar;32(3):1273-1279. doi: 10.1007/s00464-017-5803-7. Epub 2017 Aug 11.
  • Teoh AYB, Chong CCN, Leung WW, Chan SKC, Tse YK, Ng EKW, Lai PBS, Wu JCY, Lau JYW.
    Electroacupuncture-reduced sedative and analgesic requirements for diagnostic EUS: a prospective, randomized, double-blinded, sham-controlled study.
    Gastrointest Endosc. 2018 Feb;87(2):476-485. doi: 10.1016/j.gie.2017.07.029. Epub 2017 Jul 24.
  • Chong CCN, Teoh AYB, Tang RSY, Chan AWH, Ng EKW, Lai PBS.
    EUS-FNA using 22G nitinol or ProCore needles without on-site cytopathology.
    Endosc Ultrasound. 2018 Jan-Feb;7(1):56-60. doi: 10.4103/eus.eus_113_17.
  • Chan SM, Teoh AYB, Yip HC, Wong VWY, Chiu PWY, Ng EKW.
    Feasibility of per-oral cholecystoscopy and advanced gallbladder interventions after EUS-guided gallbladder stenting.
    Gastrointest Endosc. 2017 Jun;85(6):1225-1232. doi: 10.1016/j.gie.2016.10.014. Epub 2016 Oct 15.
  • Ngamruengphong S, Inoue H, Chiu PW, Yip HC, Bapaye A, Ujiki M, Patel L, Desai PN, Hayee B, Haji A, Wong VW, Perretta S, Dorwat S, Pioche M, Roman S, Rivory J, Mion F, Ponchon T, Garros A, Nakamura J, Hata Y, Balassone V, Onimaru M, Hajiyeva G, Ismail A, Chen YI, Bukhari M, Haito-Chavez Y, Kumbhari V, Maselli R, Repici A, Khashab MA.
    Long-term outcomes of per-oral endoscopic myotomy in patients with achalasia with a minimum follow-up of 2 years: an international multicenter study.
    Gastrointest Endosc. 2017 May;85(5):927-933.e2. doi: 10.1016/j.gie.2016.09.017. Epub 2016 Sep 20. Retraction in: Gastrointest Endosc. 2018 Apr;87(4):1164.
  • Ang TL, Teoh AYB.
    Endoscopic ultrasonography-guided drainage of pancreatic fluid collections.
    Dig Endosc. 2017 May;29(4):463-471. doi: 10.1111/den.12797. Epub 2017 Feb 1. Review.
  • Chan SM, Yeung B, Chiu PW.
    DDW 2016 review: Advances in therapeutic upper gastrointestinal endoscopy.
    Dig Endosc. 2017 Mar;29(2):145-148. doi: 10.1111/den.12767. Epub 2017 Jan 22. Review.
  • Teoh AYB, Serna C, Penas I, Chong CCN, Perez-Miranda M, Ng EKW, Lau JYW.
    Endoscopic ultrasound-guided gallbladder drainage reduces adverse events compared with percutaneous cholecystostomy in patients who are unfit for cholecystectomy.
    Endoscopy. 2017 Feb;49(2):130-138. doi: 10.1055/s-0042-119036. Epub 2016 Nov 22.
  • Takeshita N, Ho KY, Phee SJ, Wong J, Chiu PW.
    Feasibility of performing esophageal endoscopic submucosal dissection using master and slave transluminal endoscopic robot.
    Endoscopy. 2017 Feb;49(S 01):E27-E28. doi: 10.1055/s-0042-121486. Epub 2017 Jan 9. No abstract available.
  • Wong JC, Tang RS, Teoh AY, Sung JJ, Lau JY.
    Efficacy and safety of novel digital single-operator peroral cholangioscopy-guided laser lithotripsy for complicated biliary stones.
    Endosc Int Open. 2017 Jan;5(1):E54-E58. doi: 10.1055/s-0042-118701.
  • Chiu PW, Inoue H, Rösch T.
    From POEM to POET: Applications and perspectives for submucosal tunnel endoscopy.
    Endoscopy. 2016 Dec;48(12):1134-1142. Epub 2016 Nov 17. Review.
  • Yip HC, Chiu PW, Chan SM, Wong VW, Teoh AY, Wong SK, Ng EK.
    Esophageal leakage after surgical repair of spontaneous rupture: successful closure with endoscopic suture device.
    Endoscopy. 2016 0;48(S 01):E344-E345. Epub 2016 Nov 16. No abstract available.
  • Mori Y, Kudo SE, Chiu PW, Singh R, Misawa M, Wakamura K, Kudo T, Hayashi T, Katagiri A, Miyachi H, Ishida F, Maeda Y, Inoue H, Nimura Y, Oda M, Mori K.
    Impact of an automated system for endocytoscopic diagnosis of small colorectal lesions: an international web-based study.
    Endoscopy. 2016 Dec;48(12):1110-1118. Epub 2016 Aug 5.
  • Poon CC, Leung B, Chan CK, Lau JY, Chiu PW.
    Design of wormlike automated robotic endoscope: dynamic interaction between endoscopic balloon and surrounding tissues.
    Surg Endosc. 2016 Feb;30(2):772-8. doi: 10.1007/s00464-015-4224-8. Epub 2015 May 28.
  • Chan SM, Wu JC, Teoh AY, Yip HC, Ng EK, Lau JY, Chiu PW.
    Comparison of early outcomes and quality of life after laparoscopic Heller's cardiomyotomy to peroral endoscopic myotomy for treatment of achalasia.
    Dig Endosc. 2016 Jan;28(1):27-32. doi: 10.1111/den.12507. Epub 2015 Aug 11.
  • Li Z, Chiu PW.
    Will the robot take over endoscopy?
    Endoscopy. 2015 Sep;47(9):773-4. doi: 10.1055/s-0034-1392420. Epub 2015 Aug 28. No abstract available.
  • Chiu PW, Lai PB.
    Endoscopic Resection for Early Gastric Cancer: What is the Limit?
    Ann Surg Oncol. 2015 Jun;22(6):1753-4. doi: 10.1245/s10434-014-4312-3. Epub 2015 Feb 10. No abstract available.
  • Kumbhari V, Tieu AH, Onimaru M, El Zein MH, Teitelbaum EN, Ujiki MB, Gitelis ME, Modayil RJ, Hungness ES, Stavropoulos SN, Shiwaku H, Kunda R, Chiu P, Saxena P, Messallam AA, Inoue H, Khashab MA.
    Peroral endoscopic myotomy (POEM) vs laparoscopic Heller myotomy (LHM) for the treatment of Type III achalasia in 75 patients: a multicenter comparative study.
    Endosc Int Open. 2015 Jun;3(3):E195-201. doi: 10.1055/s-0034-1391668. Epub 2015 Apr 13.
  • Chan DY, Dolgunov D, Lee VK, Chiu PW, So JB.
    Submucosal carcinoma of the gastroesophageal junction diagnosed after peroral endoscopic myotomy.
    Endoscopy. 2015;47 Suppl 1:E623-4. doi: 10.1055/s-0034-1393591. Epub 2015 Dec 29. No abstract available.
  • Ng JJ, Chiu PW, Shabbir A, So JB.
    Removal of a large, 40-mm, submucosal leiomyoma using submucosal tunneling endoscopic resection and extraction of specimen using a distal mucosal incision.
    Endoscopy. 2015;47 Suppl 1 UCTN:E232-3. doi: 10.1055/s-0034-1391904. Epub 2015 Jun 12. No abstract available.
  • Khashab MA, Messallam AA, Onimaru M, Teitelbaum EN, Ujiki MB, Gitelis ME, Modayil RJ, Hungness ES, Stavropoulos SN, El Zein MH, Shiwaku H, Kunda R, Repici A, Minami H, Chiu PW, Ponsky J, Kumbhari V, Saxena P, Maydeo AP, Inoue H.
    International multicenter experience with peroral endoscopic myotomy for the treatment of spastic esophageal disorders refractory to medical therapy.
    Gastrointest Endosc. 2015 May;81(5):1170-7. doi: 10.1016/j.gie.2014.10.011. Epub 2015 Jan 26.
  • Liu L, Chiu PW, Teoh AY, Lam CC, Ng EK, Lau JY.
    Endoscopic suturing is superior to endoclips for closure of gastrotomy after natural orifices translumenal endoscopic surgery (NOTES): an ex vivo study.
    Surg Endosc. 2014 Apr;28(4):1342-7. doi: 10.1007/s00464-013-3280-1. Epub 2013 Nov 7.
  • Teoh AY, Chiu PW.
    Collaboration between laparoscopic surgery and endoscopic resection: an evidence-based review.
    Dig Endosc. 2014 Jan;26 Suppl 1:12-9. doi: 10.1111/den.12193. Epub 2013 Nov 5. Review.

Upper GI Cancers

  • Wong VWY, Goto O, Gregersen H, Chiu PWY.
    Endoscopic Treatment of Subepithelial Lesions of the Gastrointestinal Tract.
    Curr Treat Options Gastroenterol. 2017 Dec;15(4):603-617. doi: 10.1007/s11938-017-0152-0. Review.
  • Yip HC, Chiu PW.
    Endoscopic diagnosis and management of early squamous cell carcinoma of esophagus.
    J Thorac Dis. 2017 Jul;9(Suppl 8):S689-S696. doi: 10.21037/jtd.2017.06.57. Review.
  • Qian Y, Wong CC, Xu J, Chen H, Zhang Y, Kang W, Wang H, Zhang L, Li W, Chu ESH, Go MYY, Chiu PWY, Ng EKW, Chan FKL, Sung JJY, Si J, Yu J.
    Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation.
    Cancer Res. 2017 Apr 15;77(8):1968-1982. doi: 10.1158/0008-5472.CAN-16-1595. Epub 2017 Feb 15.
  • Takeshita N, Ho KY, Phee SJ, Wong J, Chiu PW.
    Feasibility of performing esophageal endoscopic submucosal dissection using master and slave transluminal endoscopic robot.
    Endoscopy. 2017 Feb;49(S 01):E27-E28. doi: 10.1055/s-0042-121486. Epub 2017 Jan 9. No abstract available.
  • Chiu PW, Inoue H, Rösch T.
    From POEM to POET: Applications and perspectives for submucosal tunnel endoscopy.
    Endoscopy. 2016 Dec;48(12):1134-1142. Epub 2016 Nov 17. Review.
  • Yeung B, Chiu P, Teoh A, Zheng L, Chan S, Lam K, Tang R, Ng EK.
    An innovative ex-vivo porcine upper gastrointestinal model for submucosal tunnelling endoscopic resection (STER).
    Endosc Int Open. 2016 Oct;4(10):E1101-E1106. Epub 2016 Sep 14.
  • Yeh CM, Chang LY, Lin SH, Chou JL, Hsieh HY, Zeng LH, Chuang SY, Wang HW, Dittner C, Lin CY, Lin JM, Huang YT, Ng EK, Cheng AS, Wu SF, Lin J, Yeh KT, Chan MW.
    Epigenetic silencing of the NR4A3 tumor suppressor, by aberrant JAK/STAT signaling, predicts prognosis in gastric cancer.
    Sci Rep. 2016 Aug 16;6:31690. doi: 10.1038/srep31690.
  • Yue GG, Lee JK, Li L, Chan KM, Wong EC, Chan JY, Fung KP, Lui VW, Chiu PW, Lau CB.
    Andrographis paniculata elicits anti-invasion activities by suppressing TM4SF3 gene expression and by anoikis-sensitization in esophageal cancer cells.
    Am J Cancer Res. 2015 Nov 15;5(12):3570-87. eCollection 2015.
  • Tsang JY, Ni YB, Ng EK, Shin VY, Mak KF, Go EM, Tawasil J, Chan SK, Ko CW, Kwong A, Tse GM.
    MicroRNAs are differentially deregulated in mammary malignant phyllodes tumour.
    Histopathology. 2015 Sep;67(3):294-305. doi: 10.1111/his.12648. Epub 2015 Mar 2.
  • Lee J, Chiu PW.
    A New Clinical Model for Prediction of Nodal Metastasis for Patients with Early Gastric Cancer: Is this Good Enough?
    Ann Surg Oncol. 2015 Jul;22(7):2110-1. doi: 10.1245/s10434-015-4512-5. Epub 2015 Mar 20. No abstract available.
  • Chiu PW, Lai PB.
    Endoscopic Resection for Early Gastric Cancer: What is the Limit?
    Ann Surg Oncol. 2015 Jun;22(6):1753-4. doi: 10.1245/s10434-014-4312-3. Epub 2015 Feb 10. No abstract available.
  • Fan D, Liu SY, van Hasselt CA, Vlantis AC, Ng EK, Zhang H, Dong Y, Ng SK, Chu R, Chan AB, Du J, Wei W, Liu X, Liu Z, Xing M, Chen GG.
    Estrogen receptor α induces prosurvival autophagy in papillary thyroid cancer via stimulating reactive oxygen species and extracellular signal regulated kinases.
    J Clin Endocrinol Metab. 2015 Apr;100(4):E561-71. doi: 10.1210/jc.2014-3257. Epub 2015 Jan 16.
  • Otani K, Dong Y, Li X, Lu J, Zhang N, Xu L, Go MY, Ng EK, Arakawa T, Chan FK, Sung JJ, Yu J.
    Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer.
    J Pathol. 2014 Nov;234(3):302-15. doi: 10.1002/path.4391. Epub 2014 Aug 28.
  • Zhao J, Dong Y, Kang W, Go MY, Tong JH, Ng EK, Chiu PW, Cheng AS, To KF, Sung JJ, Yu J.
    Helicobacter pylori-induced STAT3 activation and signalling network in gastric cancer.
    Oncoscience. 2014 Jul 3;1(6):468-475. eCollection 2014.
  • Wang C, Wu WK, Liu X, To KF, Chen GG, Yu J, Ng EK.
    Increased serum chemerin level promotes cellular invasiveness in gastric cancer: a clinical and experimental study.
    Peptides. 2014 Jan;51:131-8. doi: 10.1016/j.peptides.2013.10.009. Epub 2013 Nov 22.
  • Chiu PW, Ng EK, To KF, Teoh AY, Lam CC, Chan FK, Sung JJ, Lau JY.
    Recognition of goblet cells upon endocytoscopy indicates the presence of gastric intestinal metaplasia.
    Dig Endosc. 2014 Jan;26(1):52-6. doi: 10.1111/den.12050. Epub 2013 Mar 31.
  • Chiu PW.
    Novel endoscopic therapeutics for early gastric cancer.
    Clin Gastroenterol Hepatol. 2014 Jan;12(1):120-5. doi: 10.1016/j.cgh.2013.07.037. Epub 2013 Aug 15. Review.
  • Cheng AS, Li MS, Kang W, Cheng VY, Chou JL, Lau SS, Go MY, Lee CC, Ling TK, Ng EK, Yu J, Huang TH, To KF, Chan MW, Sung JJ, Chan FK.
    Helicobacter pylori causes epigenetic dysregulation of FOXD3 to promote gastric carcinogenesis.
    Gastroenterology. 2013 Jan;144(1):122-133.e9. doi: 10.1053/j.gastro.2012.10.002. Epub 2012 Oct 8.

Upper Gastrointestinal Bleeding

  • Lau JYW, Pittayanon R, Wong KT, Pinjaroen N, Chiu PWY, Rerknimitr R, Holster IL, Kuipers EJ, Wu KC, Au KWL, Chan FKL, Sung JJY.
    Prophylactic angiographic embolisation after endoscopic control of bleeding to high-risk peptic ulcers: a randomised controlled trial.
    Gut. 2018 May 25. pii: gutjnl-2018-316074. doi: 10.1136/gutjnl-2018-316074. [Epub ahead of print]
  • Xia XF, Chiu PWY, Tsoi KKF, Chan FKL, Sung JJY, Lau JYW.
    The effect of off-hours hospital admission on mortality and clinical outcomes for patients with upper gastrointestinal hemorrhage: A systematic review and meta-analysis of 20 cohorts.
    United European Gastroenterol J. 2018 Apr;6(3):367-381. doi: 10.1177/2050640617732651. Epub 2017 Sep 14.
  • Sung JJ, Chiu PC, Chan FKL, Lau JY, Goh KL, Ho LH, Jung HY, Sollano JD, Gotoda T, Reddy N, Singh R, Sugano K, Wu KC, Wu CY, Bjorkman DJ, Jensen DM, Kuipers EJ, Lanas A.
    Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018.
    Gut. 2018 Apr 24. pii: gutjnl-2018-316276. doi: 10.1136/gutjnl-2018-316276. [Epub ahead of print]
  • Chiu PWY.
    Editorial on quality standards in upper gastrointestinal endoscopy: a position statement of the British Society of Gastroenterology (BSG) and Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland (AUGIS).
    Transl Gastroenterol Hepatol. 2018 Feb 28;3:13. doi: 10.21037/tgh.2018.01.05. eCollection 2018. No abstract available.
  • Chan SM, Lau JY.
    Can we now recommend OTSC as first-line therapy in case of non-variceal upper gastrointestinal bleeding?
    Endosc Int Open. 2017 Sep;5(9):E883-E885. doi: 10.1055/s-0043-111722. Epub 2017 Sep 12. No abstract available.
  • Liu SYW, Ng SKK, Tam YH, Yee SCH, Lai FPT, Hong CYL, Chiu PWY, Ng EKW, Ng CF.
    Clinical pattern and prevalence of upper gastrointestinal toxicity in patients abusing ketamine.
    J Dig Dis. 2017 Sep;18(9):504-510. doi: 10.1111/1751-2980.12512.
  • Chan SM, Yeung B, Chiu PW.
    DDW 2016 review: Advances in therapeutic upper gastrointestinal endoscopy.
    Dig Endosc. 2017 Mar;29(2):145-148. doi: 10.1111/den.12767. Epub 2017 Jan 22. Review.

  • Chiu PW, Joeng HK, Choi CL, Tsoi KK, Kwong KH, Lam SH, Sung JJ.
    High-dose omeprazole infusion compared with scheduled second-look endoscopy for prevention of peptic ulcer rebleeding: a randomized controlled trial.
    Endoscopy. 2016 Aug;48(8):717-22. doi: 10.1055/s-0042-107590. Epub 2016 Jun 8.
  • Chiu PW, Chan FK, Lau JY.
    Endoscopic Suturing for Ulcer Exclusion in Patients With Massively Bleeding Large Gastric Ulcer.
    Gastroenterology. 2015 Jul;149(1):29-30. doi: 10.1053/j.gastro.2015.04.054. Epub 2015 May 9. No abstract available.
  • Chiu PW, Lau JY.
    What if endoscopic hemostasis fails?: Alternative treatment strategies: surgery.
    Gastroenterol Clin North Am. 2014 Dec;43(4):753-63. doi: 10.1016/j.gtc.2014.08.006. Epub 2014 Sep 12. Review.
  • Chiu PW, Chan FK.
    Upper gastrointestinal bleeding: risk scores and clinical judgment in predicting outcomes of UGIB.
    Nat Rev Gastroenterol Hepatol. 2014 Jul;11(7):399-401. doi: 10.1038/nrgastro.2014.98. Epub 2014 Jun 17.
  • Sung JJ, Suen BY, Wu JC, Lau JY, Ching JY, Lee VW, Chiu PW, Tsoi KK, Chan FK.
    Effects of intravenous and oral esomeprazole in the prevention of recurrent bleeding from peptic ulcers after endoscopic therapy.
    Am J Gastroenterol. 2014 Jul;109(7):1005-10. doi: 10.1038/ajg.2014.105. Epub 2014 Apr 29.
  • Chan SM, Chiu PW, Teoh AY, Lau JY.
    Use of the Over-The-Scope Clip for treatment of refractory upper gastrointestinal bleeding: a case series.
    Endoscopy. 2014 May;46(5):428-31. doi: 10.1055/s-0034-1364932. Epub 2014 Feb 6.
  • Chiu PW.
    Second look endoscopy in acute non-variceal upper gastrointestinal bleeding.
    Best Pract Res Clin Gastroenterol. 2013 Dec;27(6):905-11. doi: 10.1016/j.bpg.2013.09.009. Epub 2013 Oct 5. Review.

Bariatric, Metabolic and Endocrine Surgery

  • Koh ZJ, Tai BC, Kow L, Toouli J, Lakdawala M, Delko T, Kraljević M, Huang CK, Raj P, Cheng A, Rao J, Eng A, Kosai NR, Rajan R, Kim GW, Han SM, So JBY, Kasama K, Lee WJ, Kim YJ, Wong SKH, Ikramuddin S, Shabbir A.
    Influence of Asian Ethnicities on Short- and Mid-term Outcomes Following Laparoscopic Sleeve Gastrectomy.
    Obes Surg. 2019 Feb 14. [Epub ahead of print]
  • Ohta M, Seki Y, Wong SK, Wang C, Huang CK, Aly A, Baijal M, Al-Sabah S, Udomsawaengsup S, Heo YS, Althuwaini SS, Celik A, El-Hadidi N, Sargsyan D, Gee T, Rao J, Wiradisuria ER, Oliveros E, Kitano S, Kasama K.
    Bariatric/Metabolic Surgery in the Asia-Pacific Region: APMBSS 2018 Survey.
    Obesity Surgery. 2019 Feb;29(2):534–541.
  • Hui SCN, Wong SKH, Ai Q, Yeung DKW, Ng EKW, Chu WCW.
    Observed changes in brown, white, hepatic and pancreatic fat after bariatric surgery: Evaluation with MRI.
    Eur Radiol. 2019 Feb;29(2):849-856. doi: 10.1007/s00330-018-5611-z. Epub 2018 Jul 30.
  • Lai CM, Liu SY, Wong J, Wong SK, Ng EK.
    Portomesenteric vein thrombosis following laparoscopic greater curve plication for morbid obesity.
    Obes Res Clin Pract. 2018 Nov - Dec;12(6):578-582
  • Hui SCN, So HK, Chan DFY, Wong SKH, Yeung DKW, Ng EKW, Chu WCW
    Validation of water-fat MRI and proton MRS in assessment of hepatic fat and the heterogeneous distribution of hepatic fat and iron in subjects with non-alcoholic fatty liver disease.
    Eur J Radiol. 2018 Oct;107:7-13
  • Wang S, Wu J, Ren J, Vlantis AC, Li MY, Liu SYW, Ng EKW, Chan ABW, Luo DC, Liu Z, Guo W, Xue L, Ng SK, van Hasselt CA, Tong MCF, Chen GG.
    MicroRNA-125b Interacts with Foxp3 to Induce Autophagy in Thyroid Cancer.
    Mol Ther. 2018 Sep 5;26(9):2295-2303. doi: 10.1016/j.ymthe.2018.06.015. Epub 2018 Jun 21. PubMed PMID: 30005868; PubMed Central PMCID: PMC6127503.
  • Chan LKY, Wang Y, Ng EKW, Leung PS.
    Na+ /H+ exchanger 3 blockade ameliorates type 2 diabetes mellitus via inhibition of sodium-glucose co-transporter 1-mediated glucose absorption in the small intestine.
    Diabetes Obes Metab. 2018 Mar;20(3):709-717. doi: 10.1111/dom.13151. Epub 2017 Dec 5. PubMed PMID: 29110392.
  • Wong VW, Chan WK, Chitturi S, Chawla Y, Dan YY, Duseja A, Fan J, Goh KL, Hamaguchi M, Hashimoto E, Kim SU, Lesmana LA, Lin YC, Liu CJ, Ni YH, Sollano J, Wong SK, Wong GL, Chan HL, Farrell G.
    Asia-Pacific Working Party on Non-alcoholic Fatty Liver Disease guidelines 2017-Part 1: Definition, risk factors and assessment.
    J Gastroenterol Hepatol. 2018 Jan;33(1):70-85. doi: 10.1111/jgh.13857. Review. No abstract available.

  • Baig FN, Lunenburg JTJV, Liu SYW, Yip SP, Law HKW, Ying M.
    Computer-aided assessment of regional vascularity of thyroid nodules for prediction of malignancy.
    Sci Rep. 2017 Oct 30;7(1):14350. doi: 10.1038/s41598-017-14432-7.
  • Liu SY, Kim JS.
    Bilateral axillo-breast approach robotic thyroidectomy: review of evidences.
    Gland Surg. 2017 Jun;6(3):250-257. doi: 10.21037/gs.2017.04.05. Review.
  • Lee J, Wong SK, Liu SY, Ng EK.
    Is Preoperative Upper Gastrointestinal Endoscopy in Obese Patients Undergoing Bariatric Surgery Mandatory? An Asian Perspective.
    Obes Surg. 2017 Jan;27(1):44-50. doi: 10.1007/s11695-016-2243-8.
  • Wang S, Yang S, Vlantis AC, Liu SY, Ng EK, Chan AB, Wu J, Du J, Wei W, Liu X, Liu Z, Ng SK, van Hasselt CA, Tong MC, Chen GG.
    Expression of Antioxidant Molecules and Heat Shock Protein 27 in Thyroid Tumors.
    J Cell Biochem. 2016 Nov;117(11):2473-81. doi: 10.1002/jcb.25539. Epub 2016 Aug 16.
  • Liu SY, Chu CC, Tsui TK, Wong SK, Kong AP, Chiu PW, Chow FC, Ng EK.
    Aldosterone-producing Adenoma in Primary Aldosteronism: CT-guided Radiofrequency Ablation-Long-term Results and Recurrence Rate.
    Radiology. 2016 Nov;281(2):625-634. Epub 2016 May 27.
  • Koh JC, Loo WM, Goh KL, Sugano K, Chan WK, Chiu WY, Choi MG, Gonlachanvit S, Lee WJ, Lee WJ, Lee YY, Lesmana LA, Li YM, Liu CJ, Matsuura B, Nakajima A, Ng EK, Sollano JD, Wong SK, Wong VW, Yang Y, Ho KY, Dan YY.
    Asian consensus on the relationship between obesity and gastrointestinal and liver diseases.
    J Gastroenterol Hepatol. 2016 Aug;31(8):1405-13. doi: 10.1111/jgh.13385. Review.
  • Wu E, Luk A, Wong SK, So WY, Kong A, Chow F, Zhang Y, Lam C, Ng EK.
    Health-Related Quality of Life after Bariatric Surgery and its Correlation with Glycaemic Status in Hong Kong Chinese Adults.
    Obes Surg. 2016 Mar;26(3):538-45
  • Liu SY, Lang BH.
    Revisiting robotic approaches to endocrine neoplasia: do the data support their continued use?
    Curr Opin Oncol. 2016 Jan;28(1):26-36. doi: 10.1097/CCO.0000000000000245. Review.
  • Liu SY, Ng EK.
    Robotic versus Open Thyroidectomy for Differentiated Thyroid Cancer: An Evidence-Based Review.
    Int J Endocrinol. 2016;2016:4309087. doi: 10.1155/2016/4309087. Epub 2016 Mar 16. Review.
  • Liu SY, Wong SK, Lam CC, Yung MY, Kong AP, Ng EK.
    Long-term Results on Weight Loss and Diabetes Remission after Laparoscopic Sleeve Gastrectomy for A Morbidly Obese Chinese Population.
    Obes Surg. 2015 Oct;25(10):1901-8. doi: 10.1007/s11695-015-1628-4.
  • Liu SY, Wong SK, Ng EK.
    Novel oesophago-gastro-duodenal stenting for gastric leaks after laparoscopic sleeve gastrectomy.
    Obes Res Clin Pract. 2015 May-Jun;9(3):214-9. doi: 10.1016/j.orcp.2014.11.007. Epub 2014 Dec 18.
  • Fan D, Liu SY, van Hasselt CA, Vlantis AC, Ng EK, Zhang H, Dong Y, Ng SK, Chu R, Chan AB, Du J, Wei W, Liu X, Liu Z, Xing M, Chen GG.
    Estrogen receptor α induces prosurvival autophagy in papillary thyroid cancer via stimulating reactive oxygen species and extracellular signal regulated kinases.
    J Clin Endocinol Metab. 2015 Apr;100(4):E561-71. doi: 10.1210/jc.2014-3257. Epub 2015 Jan 16.
  • Wong SK, Kong AP, Luk AO, Ozaki R, Ng VW, Lebovitz HE, Ng EK, Chan JC.
    A pilot study to compare meal-triggered gastric electrical stimulation and insulin treatment in Chinese obese type 2 diabetes.
    Diabetes Technol Ther. 2015 Apr;17(4):283-90. doi: 10.1089/dia.2014.0234. Epub 2015 Feb 24.
  • Chu R, Liu SY, Vlantis AC, van Hasselt CA, Ng EK, Fan MD, Ng SK, Chan AB, Du J, Wei W, Liu X, Liu Z, Chen GG.
    Inhibition of Foxp3 in cancer cells induces apoptosis of thyroid cancer cells.
    Mol Cell Endocrinol. 2015 Jan 5;399:228-34. doi: 10.1016/j.mce.2014.10.006. Epub 2014 Oct 12.
  • Lee RK, Liu SY, Tong CS, Lee PS, Ng EK, Ahuja AT.
    Morphologic change in computed tomography of aldosterone-producing adenoma after radiofrequency ablation.
    Can Assoc Radiol J. 2014 Feb;65(1):86-90. doi: 10.1016/j.carj.2012.12.006. Epub 2013 May 22.
  • Chu R, van Hasselt A, Vlantis AC, Ng EK, Liu SY, Fan MD, Ng SK, Chan AB, Liu Z, Li XY, Chen GG.
    The cross-talk between estrogen receptor and peroxisome proliferator-activated receptor gamma in thyroid cancer.
    Cancer. 2014 Jan 1;120(1):142-53. doi: 10.1002/cncr.28383. Epub 2013 Oct 2.
  • Lee WJ, Hur KY, Lakadawala M, Kasama K, Wong SKH, Lee YC, Ser KH.
    Predicting the Success of Metabolic Surgery: Age, Body Mass Index, C-peptide, and Duration Score.
    Surgery for Obesity and Related Diseases 2013 May-Jun;9(3):379-84
  • Wong SKH, Kong APS, So WY, Tsung BYS, Yau PYP, Chan JCN, Ng EKW.
    Use of laparoscopic sleeve gastrectomy and adjustable gastric banding for suboptimally controlled diabetes in Hong Kong.
    Diabetes, Obesity and Metabolism 2012 Apr;14(4): 372–374.
  • Liu SY, Ng EK, Lee PS, Wong SK, Chiu PW, Mui WL, So WY, Chow FC.
    Radiofrequency ablation for benign aldosterone-producing adenoma: a scarless technique to an old disease.
    Ann Surg. 2010 Dec;252(6):1058-64. doi: 10.1097/SLA.0b013e318f66936.

Copyright © 2024. All Rights Reserved. Department of Surgery, The Chinese University of Hong KongCUHK

C O N T A C T   U S

Peroral Endoscopic Myotomy

ICG Guided Minimally Invasive Oesophagectomy

EUS Guided Gallbladder Drainage

EUS Guided Gastroenterostomy

3D Laparoscopic Surgery

Robotic Gastrectomy

CUHK Endoluminal Robotics platform won 47th International Exhibition of Inventions of Geneva Gold Medal (Gold Medal with Congratulations of the Jury) 2019

The Scalpel and the Brush - June 2019

CUHK Successfully Performed Hong Kong's First Robotic Endoscopic Scarless Surgery - A Major Endoscopic Technological Breakthrough - 15 December 2011

CUHK Pioneers Scarless Per-oral Endoscopic Myotomy for Treatment of Esophageal Motility Disorders in Hong Kong - 20 January 2011