Dr CHAN Shannon Melissa    
陳詩瓏

Associate Professor
MBChB (CUHK), FRCSEd (Gen), FCSHK, FHKAM (Surgery), FJGES

Upper Gastrointestinal and Metabolic Surgery
(852) 3505 2957
shannonchanadd this for spam@add this for spamsurgery.cuhk.edu.hk

Biography

Dr Shannon Chan is currently an Associate Professor and Head of Division of Upper Gastrointestinal & Metabolic Surgery of The Chinese University of Hong Kong. She graduated from the Chinese University of Hong Kong in 2007. She completed general surgical training and received fellowships of the College of Surgeons of Hong Kong and Royal College of Surgeons of Edinburgh in 2014. Dr. Chan’s interest is in gastric and esophageal cancers, mainly focusing in the laparoscopic and robotic approach. She did her overseas training in National Cancer Centre in Tokyo, Yonsei University in Seoul and also Amsterdam Medical Centre in Amsterdam. Her research interests include upper gastrointestinal surgical oncology and advanced diagnostic and therapeutic endoscopy especially in interventional endoscopic ultrasound. She also has special interests in peritoneal surface malignancy and has started a multidisciplinary team for these rare, yet important group of patients. She is a member of the stomach and duodenal diseases subcommittee of the World Endoscopy Organisation (WEO) and is a reviewer for Digestive Endoscopy and Surgical Endoscopy. She has published over 20 peer-reviewed journals.  

Apart from her research interest, Dr. Chan has also devoted herself to humanitarian aid work. In 2014, she joined the Médecins Sans Frontières (MSF, also named Doctors without borders). MSF is an international humanitarian non-governmental organization working in war-torn and under-developed regions. Dr. Chan joined their surgical missions to South Sudan from Oct 2016 - Dec 2016 and to Yemen from Dec 2019 to Feb 2020. After her return, she has further affirmed her commitment to providing humanitarian aid to the less developed parts of the world.

Research Interests

• Interventional endosonography and Endoscopic Retrograde Cholangiography
• Robotics and Minimal invasive surgery for UGI cancers
• Peritoneal Surface Malignancy
• Endoscopic management of upper gastrointestinal bleeding
• Endoscopic submucosal dissection and novel endoscopic resectional techniques
• Artificial Intelligence (AI) in UGI

Selected Publications

1. Chan AHY, Fok JCY, Ng SKK, Chan SM. Case of gallstone ileus and dislodged stent post endoscopic gallbladder drainage. Endoscopy 2026 Mar;58:E402-E403. doi: 10.1055/a-2820-3915.
2. Vanella G, Frigo F, Bronswijk M, van Wanrooij RLJ, Chen Y, Binmoeller KF, Perez-Miranda M, Leone R, Chahal P, Chan SM, Jovani M, Tyberg A, Pérez-Cuadrado-Robles E, Sharaiha R, Barthet M, Deprez P, Baron T, Kahaleh M, Adler DG, Khashab M, Teoh AYB, Itoi T, Lakhtakia S, Kunda R, Van der Merwe S, Arcidiacono PG. Standardizing Success and Troubleshooting in EUS-Guided Gastroenterostomy. Journal of Clinical Gastroenterology 2026 Mar; 60(3): 197-215. doi: 10.1097/MCG.0000000000002242.
3. Mosko JD, Al-Haddad M, Pohl H, Kumta NA, Chan SM, Ryou M, Nabi Z, Zhou PH, Inoue H, Peetermans JA, Rousseau MJ, von Renteln D. Through-the-scope clip with anchor prongs for defect closure following myotomy, resection, anti-reflux mucosectomy, fistula management, or bleeding. Endosc Int Open 2026 Jan; 14. doi: 10.1055/a-2773-4910.
4. Hau SF, Chan SM. Endoscopic full-thickness resection of upper gastrointestinal tract: a review on closure techniques. Clinical Endoscopy 2025 Sep. doi: 10.5946/ce.2025.037.
5. Yuen R, Lam B, Chan SM, Yip HC, Teoh AYB. Comparison of Direct Endoscopic Necrosectomy With Endoscopic Step-Up Approach After Endoscopic Drainage of Pancreatic Walled-Off Necrosis: Systematic Review and Meta-Analysis. Digestive Endoscopy 2025 Dec; 37(12):1286-1294. doi: 10.1111/den.70021
6. Dong ZW, Zhou SR, Xia XF, Yip HC, Leung KKC, Chan SM, Chiu PWY. Mesenchymal stem cell-derived small extracellular vesicles facilitate repair of acute obstruction-induced colonic anastomosis injury by modulating early-stage inflammation in rats. Stem Cell Research & Therapy 2025 Aug; 16(1). doi: 10.1186/s13287-025-04551-8.
7. Crinò SF, Aabakken L, Bapaye A, Chan SM, Kida M, Law, R, Maluf F, Mekaroonkamol P, de Moura EGH, Bestetti A, Mostafa I, Park D, Rajaram RB, Reddy ND, Seo DW, Pittayanon R, Teoh AYB. World Endoscopy Organization guidelines on endoscopic retrograde cholangiopancreatography biliary cannulation and sphincterotomy techniques. Digestive Endocscopy 2025 Oct; 37(10): 1029-1053. doi: 10.1111/den.15060.
8. Teoh AYB, Lakhtakia S, Perez-Miranda M, Maluf F, Dhir V, Basha J, Chan SM, Ligresti D, Ma MTW, de la Serna-Higuera C, Yip HC, Ng EKW, Chiu PWY, Itoi T. Endoscopic ultrasonography-guided gastroenterostomy versus uncovered duodenal metal stenting for unresectable malignant gastric outlet obstruction (DRA-GOO) a multicentre randomised controlled trial. Lancet Gastroenterology & Hepatology 2025 Jun; 10(6): e8-e16. doi: 10.1016/S2468-1253(25)00136-0.
9. Chan SM, Daniel Chan, Hon Chi Yip, Markus Wolfgang Scheppach, Ray Lam, Stephen KK Ng, Enders Kwok Wai Ng, Philip W Chiu. Artificial intelligence-assisted esophagogastroduodenoscopy improves procedure quality for endoscopists in early stages of training. Endosc Int Open 2025 Apr; 13:a25476645. doi: 10.1055/a-2547-6645.
10. Fok JCY, Teoh AYB, Chan SM. Endoscopic ultrasound-guided gallbladder drainage for acute cholecystitis. Dig Endosc. 2025 Jan;37(1):93-102. doi: 10.1111/den.14946. Epub 2024 Nov 18.PMID: 39552245