|The 2016 State Science and Technology Awards ceremony was held today (9 January) at the Great Hall of the People in Beijing. The Chinese University of Hong Kong (CUHK) received six awards, including one State Natural Science Award (SNSA) second-class, one State Scientific and Technological Progress Award (SSTPA) first-class, three SSTPA second-class awards as well as, for the first time, the SSTPA (Innovation Team).
The State Natural Science Award second-class award - Integrative Research on Molecular Pathogenesis, Diagnostic Biomarkers and Prevention for Colorectal Cancer
Prof. Joseph JY Sung, Vice-Chancellor and President of CUHK and Mok Hing Yiu Professor of Medicine, Prof. Jun Yu, Professor of the Department of Medicine and Therapeutics, Prof. Francis KL Chan, Dean of the Faculty of Medicine, Dr. William KK Wu, Assistant Professor of the Department of Anaesthesia and Intensive Care and the Institute of Digestive Diseases, and Prof. Simon SM Ng, Professor of the Department of Surgery, were honoured with the SNSA second-class award for the project entitled 'Integrative Research on Molecular Pathogenesis, Diagnostic Biomarkers and Prevention for Colorectal Cancer'.
Colorectal cancer (CRC) is one of the most common malignancies. The research team led by Prof. Joseph JY Sung has been investigating the epidemiology, screening, molecular pathogenesis and biomarkers of CRC for 15 years. The team has achieved several breakthroughs, including leading an Asia-Pacific working group to study the epidemiology and risk factors of CRC and formulating a guideline on CRC screening; unveiling the mutational landscape of CRC in the Chinese population and discovering new fusion genes and high-frequency mutated genes; identifying novel epigenetic alterations and signaling pathway dysregulation in CRC; and identifying novel biomarkers for non-invasive diagnosis of CRC.